| The Ginkgo biloba
or maidenhair tree is a living fossil that is touted as an elixir of
youth. It is the last living species of the family Ginkgoaceae, having
survived unchanged in China for more than 200 million years. The name
ginkgo comes from the Chinese yinkuo, meaning "silver fuit" and
biloba means "two lobes", in reference to the young leaves which are
distinctly two-lobed. Ginkgo trees were brought to the western
hemisphere in the 1700’s and have since become a popular hardy,
ornamental tree throughout the world. For almost five thousand years the
Chinese have revered ginkgo nuts as medicine, but only recently have the
leaves been utilized. Ginkgo biloba extracts are made from
freshly-picked green leaves that are picked in the fall just before the
leaves turn yellow in order to get the maximum levels of constituents.
Ginkgo biloba leaves contain a complex array of chemical constituents
including flavonoids, terpenoids, organic acids, carotenoids, and
sterols. Of particular interest are the terpenoids, mainly a unique
group of diterpenes known as ginkgolides and sesquiterpenes known as
bilobalides, as well as the flavonoids, mostly flavonoid glycosides
including quercetin, kaempferol, and isorhamnetin. Other flavonoid
groups include coumarin esters of quercetin and kaempferol,
proanthocyanidins, catechins, and condensed tannins. Ginkgo is an
anti-oxidant which inhibits free-radicals, major contributors to the
aging process, preventing damage in tissues , such as the eyes, ears,
brain, and extremities. Ginkgo promotes vasodilation and improves blood
flow in both arteries and capillaries. Ginkgo increases blood flow to
the brain bringing better oxygenation and glucose supply to cerebral
tissues, particularly in geriatric patients. Ginkgo may improve memory
and awareness by enhancing neurotransmitter binding such as
acetylcholine binding to muscarinic receptors, which may allay
age-related cognitive disorders such as Alzheimer’s disease. Ginkgo has
been used for conditions such as short-term memory loss, headache,
tinnitus, depression, etc. Ginkgo also inhibits PAF (Platelet Activating
Factor) which activates several types of immune cells, including
neutrophils, eosinophils, and macrophages, and endothelial cells. All of
these cells secrete chemicals which cause inflammation as well as
enhance the blood clotting process. If production of PAF is
overstimulated (which can happen under chronic stressful conditions such
as poor diet or exposure to environmental allergens) then the immune
system can go haywire producing conditions like asthma and other
allergic responses. Ginkgo may also protect the retina and cornea, aid
macular degeneration and treat dizziness and equilibrium disorders.
Ginkgo biloba should not be taken with other anticoagulant drugs and
should be discontinued before surgery . |
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