| Vitex or chaste tree berries
are the dried fruits of Vitex agnus castus, a species from the
Verbanaceae family which is native to Greece and Italy. It grows as a
shrub along Mediterranean regions but can grow to the size of a small
tree. The leaves are opposite with five to seven palmately compound
leaflets. The bark is white-felted and the flowers are colored spikes
of white and lilac-to-blue. The fruits are small, hard, reddish-black
to gray drupes which have been used as medicine since the times of
ancient Greece. The Greek name "agnos castos" means "chaste as a
lamb", referring to its ancient use for calming sexual desires. It was
also called "Monk’s pepper" in Germany for the same reason.
Traditionally it was touted as a remedy for female imbalances. Modern
interest in vitex is due to the plant’s effect on the female hormonal
system. It has been proven that vitex increases milk flow in nursing
mothers, demonstrating a galactogogue effect. Later it was found that
vitex also helps treat menstrual disorders including heavy menstrual
bleeding and very short menstrual cycles as well as general symptoms
of PMS (pre-menstrual syndrome), endometriosis, fibrocystic disease,
premenopausal symptoms, corpus luteum insufficiency, and pubescent
acne (including men). Major symptoms of PMS aided by vitex include
emotional depression, acne/skin rashes, mastitis, uterine cramps,
migraines, heart pains, abdominal cramping, edema, and change in
appetite. Vitex works by helping to balance the female sexual
hormones. It is thought that it does this by regulating the pituitary
gland, which is the master gland of the endocrine system. It sends
chemical messages to other glands that specify how much of a
particular hormone to secrete. Sensors elsewhere in the body detect
the levels which are then regulated by negative feedback. It appears to
indirectly stimulate progesterone production through the anterior lobe
of the pituitary gland. It also has an estrogenic effect and thus is
effective in treating menstrual complaints as well as constipation and
acne. Research shows that vitex restores a normal
estrogen-to-progesterone balance. In addition, vitex stimulates the
secretion of luteinizing hormone (LH) and luteotropic hormone (LTH),
thus stimulating formation of the corpeus luteum, and it inhibits
prolactin and follicle-stimulating hormone (FSH). There are three main
components of vitex that are thought to be responsible for these
actions, which include an essential oil, iridoid glycosides, and a
flavone. The essential oil is mainly composed of cineol,
a- &
b-pinene,
and limonene. The iridoid glycosides are aucubin and agnuside; and the
flavone is casticin. There are also some minor flavonoids present.
Vitex can be taken safely through the end of the third month of
pregnancy and has been used traditionally to prevent miscarriage.
Because it is a galactogogue, it may bring on the flow of milk too
early, so it is recommended to stop usage after three months. It has
been used preventatively in treatment of endometriosis, but not until
treatment with synthetic progesteronal drugs restores menstruation,
then it is taken to prevent further complications. During menopause
when progesterone levels decrease, vitex can help reduce some of the
symptoms such as hot flashes, depression, and vaginal dryness. Vitex
has been used safely without side effects for over 2,000 years. It
should not be taken with progesterone or progesterone-like drugs (such
as birth control) as it may interfere with the drug’s action. Vitex
creates a change in the body’s cyclic hormonal balance, acting gently
and slowly to bring a positive change and requires long-term,
continued use to receive the full, beneficial effects. |
|